Iron deficiency anemia

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NEW TREATMENT ADDED BY A MEMBER
20 Studies
Iron Supplements
Fast way to get more iron into the body.
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completely cured
significant improvement
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Helps with prevention
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ESSENTIAL RESEARCH
Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial.
Routine supplementation with iron and folic acid in preschool children in a population with high rates of malaria can result in an increased risk of severe illness and death. In the presence of an active programme to detect and treat malaria and other infections, iron-deficient and anaemic children can benefit from supplementation. However, supplementation of those who are not iron deficient might be harmful. As such, current guidelines for universal supplementation with iron and folic acid should be revised.
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NEW SYMPTOM ADDED BY A MEMBER
Yes
3
No
0
Difficulty paying attention or focusing
100% reported this symptom
Mind drifts or blanks out.
PROGRESS UPDATE
SYMPTOM
Fatigue marked as mild
Cold Feet marked as minimal
Cold Hands marked as mild
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0REPLY1 YEAR AGO
CLINICAL TRIALNot yet recruiting
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability
Zurich, Switzerland
Female
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products. However, animal products are a key dietary source of well-absorbed iron, and iron deficiency and iron deficiency anemia remain highly prevalent in high- and low-income countries. Meat and fish provide a substantial proportion of absorbed iron in the western diet by two distinct components: a) heme iron is well absorbed (20-45% fractional absorption) and is not affected by most dietary enhancers and inhibitors, which often affect non-heme iron absorption; b) peptides in muscle meat exert an enhancing effect the absorption of non-heme iron contained in other meal components. The potential of edible insects as a dietary source of well-absorbed iron has not been investigated in detail. In particular, it is unclear whether insects provide an iron moiety similar to hemoglobin which would be well absorbed and unaffected by other dietary components, and whether their presence in a test meal exerts an enhancing effect on iron bioavailability from the whole meal. Furthermore, chitin, a major component of insect biomass, is a known iron binder and is potentially responsible for a decreased iron absorption from insect-based foods. Decreasing chitin content could allow the high amounts of iron in insects to be well-absorbed, and enhance the absorption of iron from plant-based foods. To differentiate iron absorption from insect biomass from other sources, insects will be intrinsically labelled with the stable iron isotope 57Fe, while other food iron components will be labelled with the iron isotope 58Fe.The present study will provide novel data to elucidate the nutritional value as sources of dietary iron of insect species (Tenebrio molitor). Since 2017 T.molitor is recognised as an edible insect in the Swiss food legislation and commercially available (Essento Food AG, Zürich; Insekterei, GmbH, Zürich).
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0REPLY1 YEAR AGO
ESSENTIAL RESEARCH
Ferric carboxymaltose in patients with heart failure and iron deficiency.
Treatment with intravenous ferric carboxymaltose in patients with chronic heart failure and iron deficiency, with or without anemia, improves symptoms, functional capacity, and quality of life; the side-effect profile is acceptable. (ClinicalTrials.gov number, NCT00520780).
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ESSENTIAL RESEARCH
Prevalence of iron deficiency in the United States.
Iron deficiency and iron deficiency anemia are still relatively common in toddlers, adolescent girls, and women of childbearing age.
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NEW SYMPTOM ADDED BY A MEMBER
Yes
3
No
0
Fatigue
100% reported this symptom
Fatigue is a subjective feeling of tiredness which is distinct from weakness, and has a gradual onset.
ESSENTIAL RESEARCH
Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy.
Severe, chronic iron deficiency in infancy identifies children who continue at developmental and behavioral risk >10 years after iron treatment.
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CLINICAL TRIALNot yet recruiting
Iron Deficiency as an Ignored Cause of Infertility
Helsinki, Finland
Female
Phase 4
Iron deficiency may play a critical role in human infertility, oocyte quality and may even play a role in endometrial receptivity. By correcting iron deficiency, low ferritin values, in infertile women with intravenous iron supplementation, embryo quality and pregnancy rates may improve. The main objective is to evaluate the effect of intravenous iron supplementation on embryo quality (number of good quality blastocysts). Randomized, double blind, parallel group, cross-over study of ferric carboxymaltose compared to placebo (NaCl infusion).
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0REPLY1 YEAR AGO
PROGRESS UPDATE
TREATMENT
Iron Supplements made a significant improvement
SYMPTOM
Cold Hands marked as moderate
Fatigue changed from moderate to moderate.
0REPLY3 YEARS AGO
ESSENTIAL RESEARCH
Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis.
Measures of both APP and CRP are needed to estimate the full effect of inflammation and can be used to correct ferritin concentrations. Few differences were observed between age and sex subgroups.
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ESSENTIAL RESEARCH
The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire.
Anemic African children carry an unfavorable ratio of fecal enterobacteria to bifidobacteria and lactobacilli, which is increased by iron fortification. Thus, iron fortification in this population produces a potentially more pathogenic gut microbiota profile, and this profile is associated with increased gut inflammation. This trial was registered at controlled-trials.com as ISRCTN21782274.
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ESSENTIAL RESEARCH
Severe anemia in Malawian children.
There are multiple causes of severe anemia in Malawian preschool children, but folate and iron deficiencies are not prominent among them. Even in the presence of malaria parasites, additional or alternative causes of severe anemia should be considered.
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CLINICAL TRIALCompleted
A Trial Comparing Ferumoxytol With Placebo for the Treatment of Iron Deficiency Anemia
182 Locations
All genders
Phase 3
To evaluate the efficacy and safety of intravenous (IV) ferumoxytol compared with placebo for the treatment of iron deficiency anemia (IDA).
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0REPLY1 YEAR AGO
ESSENTIAL RESEARCH
Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis.
Daily prenatal use of iron substantially improved birth weight in a linear dose-response fashion, probably leading to a reduction in risk of low birth weight. An improvement in prenatal mean haemoglobin concentration linearly increased birth weight.
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ABOUT
Too few healthy red blood cells due to too little iron in the body.Wikipedia
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