Ulcerative colitis

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NEW TREATMENT ADDED BY A MEMBER
17 Studies
Probiotics (probiotic)
Beneficial bacteria for the gut.
6 studies show it's effective
53% of users reported improvements
Home Remedy
OTC
TRIED
TRYING
How effective is it?
REMOVE ANSWER
completely cured
significant improvement
minor improvement
no difference
worse than before
Helps with prevention
2 (6%)
8 (22%)
9 (25%)
15 (42%)
2 (6%)
ESSENTIAL RESEARCH
Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review.
Although there are few epidemiologic data from developing countries, the incidence and prevalence of IBD are increasing with time and in different regions around the world, indicating its emergence as a global disease.
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NEW SYMPTOM ADDED BY A MEMBER
Yes
11
No
1
Blood in stool
92% reported this symptom
The occurance of blood in stool.
Can H pylori cause frequent urination and also a feeling of dry eyes
Been also battling with Ulcer for over one month now.
0REPLY1 YEAR AGO
PROGRESS UPDATE
SYMPTOM
Blood in stool marked as moderate
0REPLY1 YEAR AGO
CLINICAL TRIALRecruiting
Pro-active Fecal Calprotectin Monitoring PROMOTE-UC
Vancouver, Canada
All genders
Hypothesis: Pro-active home fecal calprotectin testing in patients with Ulcerative Colitis will allow early detection and treatment of inflammation to prevent symptomatic flares. This will result in less steroid use, fewer hospitalizations and a reduced risk of surgery, as well as improved quality of life and adherence to medication.
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0REPLY1 YEAR AGO
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ESSENTIAL RESEARCH
Infliximab for induction and maintenance therapy for ulcerative colitis.
Patients with moderate-to-severe active ulcerative colitis treated with infliximab at weeks 0, 2, and 6 and every eight weeks thereafter were more likely to have a clinical response at weeks 8, 30, and 54 than were those receiving placebo. (ClinicalTrials.gov numbers, NCT00036439 and NCT00096655.)
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ESSENTIAL RESEARCH
The risk of colorectal cancer in ulcerative colitis: a meta-analysis.
Using new meta-analysis techniques we determined the risk of CRC in UC by decade of disease and defined the risk in pancolitics and children. We found a non-significant increase in risk over time and estimated how risk varies with geography.
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NEW TREATMENT ADDED BY A MEMBER
Mesalamine (Canasa, Apriso, Lialda, Pentasa, Asacol HD, sfRowasa, and Delzicol)
Prescription drug used to treat ulcerative colitis.
74% of users reported improvements
Prescription
TRIED
TRYING
How effective is it?
REMOVE ANSWER
completely cured
significant improvement
minor improvement
no difference
worse than before
Helps with prevention
2 (6%)
10 (29%)
14 (40%)
5 (14%)
4 (11%)
NEW SYMPTOM ADDED BY A MEMBER
Yes
7
No
2
Stomach ache (Abdominal Pain)
78% reported this symptom
Pain in the stomach.
ESSENTIAL RESEARCH
Increased expression of interleukin 17 in inflammatory bowel disease.
IL-17 expression in the mucosa and serum was increased in IBD patients. It is likely that IL-17 expression in IBD may be associated with altered immune and inflammatory responses in the intestinal mucosa.
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CLINICAL TRIALRecruiting
A Clinical Study to Assess the Affects of KB295 in Patients With Ulcerative Colitis (UC) on Gut Microbiota Structure and Function
Cork, Ireland
All genders
This exploratory, open-label clinical study aims to explore the effects of KB295, a novel glycan, on adult patients with ulcerative colitis (UC) presenting with mild-to-moderate UC symptoms
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0REPLY1 YEAR AGO
NEW TREATMENT ADDED BY A MEMBER
34 Studies
Adrenal cortex hormones (corticosteroids, corticoids)
Common treatment for colitis.
1 study shows it's effective
86% of users reported improvements
Prescription
TRIED
TRYING
How effective is it?
REMOVE ANSWER
completely cured
significant improvement
minor improvement
no difference
worse than before
Helps with prevention
5 (17%)
13 (45%)
7 (24%)
3 (10%)
1 (3%)
PROGRESS UPDATE
TREATMENT
Probiotics made a minor improvement
0REPLY1 YEAR AGO
ESSENTIAL RESEARCH
ESSENTIAL RESEARCH
Ulcerative colitis and colorectal cancer. A population-based study.
Close surveillance and perhaps even prophylactic proctocolectomy should be recommended for patients given a diagnosis of pancolitis, especially those who are less than 15 years of age at diagnosis.
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ESSENTIAL RESEARCH
Low counts of Faecalibacterium prausnitzii in colitis microbiota.
The fecal microbiota of patients with IBD differs from that of HS. The phylum Firmicutes and particularly the species F. prausnitzii, are underrepresented in A-IBD patients as well as in IC patients. These bacteria could be crucial to gut homeostasis since lower counts of F. prausnitzii are consistently associated with a reduced protection of the gut mucosa.
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CLINICAL TRIALNot yet recruiting
A Fasting Mimicking Diet on Ulcerative Colitis Patients Undergoing Tofacitinib Induction
2 Locations
All genders
Phase 3
The purpose of this study is to determine whether a diet intervention (the Fasting Mimicking diet) will help induce clinical and biochemical response to tofacitinib therapy in patients with ulcerative colitis. Study period will be 8 weeks during induction of tofacitinib. The primary aims of this study are to determine clinical response and improvement in fecal calprotectin and C-reactive protein levels. Secondary outcomes will include assessment of changes in the stool microbiome.
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0REPLY1 YEAR AGO
ESSENTIAL RESEARCH
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.
IL-13 was identified as an important effector cytokine in UC that impairs epithelial barrier function by affecting epithelial apoptosis, tight junctions, and restitution velocity.
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ABOUT
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum. The primary symptom of active disease is abdominal pain and diarrhea mixed with blood. Weight loss, fever, and anemia may also occur. Often symptoms come on slowly and can range from mild to severe. Symptoms typically occur intermittently with periods of no symptoms between flares. Complications may include megacolon, inflammation of the eye, joints, or liver, and colon cancer.Wikipedia
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